About memantine hydrochloride
NMDA receptor antagonist
Used for
- Treatment of moderate to severe Alzheimer’s disease.
Usual adult dose
Usually increased gradually to 20 mg daily, taken as 10 mg twice daily.
Common side effects
- Dizziness
- Headache
- Confusion
- Constipation
Important warnings
- Use caution with seizures, kidney problems, or conditions that change urine acidity.
- Dose reduction may be needed in severe kidney impairment.
- May impair driving or tasks requiring alertness.
Pregnancy
Human pregnancy information is limited; use only when clearly needed.
Breastfeeding
It is unknown whether memantine passes into breast milk; breastfeeding is generally not recommended during treatment.
Interactions
- Amantadine, ketamine, or dextromethorphan may increase nervous-system effects.
- Urine-alkalinizing medicines, including sodium bicarbonate, may raise memantine levels.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.