About mefenamic acid
Nonsteroidal anti-inflammatory drug (NSAID)
Used for
- Short-term relief of mild to moderate pain
- Menstrual cramps
Usual adult dose
Usually 500 mg three times daily with food; use for the shortest time needed.
Usual dose in children
For ages 14 and older: usually 500 mg three times daily. Not generally used below age 14.
Common side effects
- Stomach pain, indigestion, nausea, or diarrhea
- Dizziness or headache
- Stomach ulcers or bleeding
- Kidney problems or allergic reactions
Important warnings
- Can cause serious stomach bleeding, ulcers, or perforation.
- May increase risks of heart attack and stroke, especially with prolonged use.
- Avoid with other NSAIDs; extra caution with kidney disease, ulcers, or blood thinners.
- Do not use for pain around coronary artery bypass surgery.
Pregnancy
Avoid from 20 weeks unless specifically directed; avoid from 30 weeks because of fetal heart risks.
Breastfeeding
Small amounts may enter milk; seek professional guidance, especially for newborn or premature infants.
Interactions
- Warfarin and other anticoagulants increase bleeding risk.
- Other NSAIDs, including ibuprofen and naproxen, increase side effects.
- Aspirin may increase bleeding and stomach irritation.
- Lithium, methotrexate, diuretics, and some blood pressure medicines may interact.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.