About mefenamic acid
Nonsteroidal anti-inflammatory drug (NSAID)
Used for
- Short-term relief of mild to moderate pain
- Painful menstrual periods
Usual adult dose
Usually 500 mg initially, then 250 mg every six hours as needed; use for the shortest duration.
Usual dose in children
For children aged 14 years and older: usually 500 mg initially, then 250 mg every six hours as needed. Not recommended below age 14.
Common side effects
- Stomach pain, nausea, diarrhea, or indigestion
- Dizziness or headache
- Stomach ulcer or bleeding
- Kidney problems or allergic reactions
Important warnings
- Can cause serious stomach bleeding, ulcers, or perforation.
- May increase the risk of heart attack or stroke.
- Avoid with other NSAIDs, such as ibuprofen or naproxen.
- Use cautiously with kidney disease, heart disease, asthma, or older age.
Pregnancy
Avoid from 20 weeks unless specifically directed; avoid after 30 weeks because of fetal risks.
Breastfeeding
Small amounts may enter breast milk; seek professional guidance, especially for newborn or premature infants.
Interactions
- Blood thinners and antiplatelet medicines can increase bleeding.
- Other NSAIDs or aspirin can increase stomach and kidney risks.
- ACE inhibitors, ARBs, and diuretics may worsen kidney function.
- Lithium and methotrexate levels may increase.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.