About mava camt
Cardiac myosin inhibitor
Used for
- Treats adults with symptomatic obstructive hypertrophic cardiomyopathy to improve symptoms and physical function.
Usual adult dose
Usually 2.5 mg by mouth once daily; dosing is adjusted using heart ultrasound results, up to 15 mg daily.
Common side effects
- Dizziness
- Fainting
- Heart failure
Important warnings
- Can weaken heart pumping and cause serious or life-threatening heart failure.
- Regular heart ultrasound monitoring is required before and during treatment.
- Avoid in pregnancy; effective contraception is needed during treatment and for four months afterward.
- Do not start or stop interacting medicines without clinical review.
Pregnancy
May cause fetal harm. Avoid pregnancy during treatment and for four months after the last dose.
Breastfeeding
It is unknown whether mavacamten passes into breast milk; breastfeeding is not recommended during treatment and for four months afterward.
Interactions
- Several medicines can raise mavacamten levels, including clarithromycin, ketoconazole, and ritonavir.
- Some medicines can lower levels, including rifampin, carbamazepine, and St John’s wort.
- Combining with disopyramide, ranolazine, or certain calcium-channel blockers can increase heart-failure risk.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.