About mafenide acetate
Topical sulfonamide antibacterial
Used for
- Prevention and treatment of infection in severe burns.
Usual adult dose
Apply a 1/16-inch layer to burn wounds once or twice daily; continue until grafting or healing.
Usual dose in children
Same as adult dose; dosing is based on wound area, not age.
Common side effects
- Burning or pain at application site
- Rash or itching
- Metabolic acidosis
- Rapid breathing
Important warnings
- Can cause metabolic acidosis, especially with extensive burns or kidney problems.
- Sulfonamide allergy may increase risk of allergic reactions.
- May slow healing of some wounds.
- Use only on burn wounds as directed by a clinician.
Pregnancy
Use only when clearly needed; safety in pregnancy is not well established.
Breastfeeding
It is unknown whether mafenide enters breast milk; use caution during breastfeeding.
Interactions
- No major drug interactions are well established.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.