About lurasidone hcl
Second-generation antipsychotic
Used for
- Schizophrenia in adults and adolescents
- Bipolar depression in adults and children
Usual adult dose
Schizophrenia: usually 40–160 mg once daily with food. Bipolar depression: usually 20–120 mg once daily with food.
Usual dose in children
Schizophrenia, ages 13–17: usually 40–80 mg once daily. Bipolar depression, ages 10–17: usually 20–80 mg once daily, with food.
Common side effects
- Nausea
- Sleepiness or restlessness
- Movement problems, including stiffness or tremor
- Weight or blood sugar changes
Important warnings
- Can cause serious movement disorders, including tardive dyskinesia
- May increase blood sugar and cholesterol
- Can cause dizziness or fainting, especially when standing
- Not approved for dementia-related psychosis; increased death risk in older adults
Pregnancy
May cause newborn movement or withdrawal symptoms if used during the third trimester. Discuss risks and benefits with a healthcare professional.
Breastfeeding
Lurasidone enters breast milk in small amounts; effects on a nursing infant are uncertain.
Interactions
- Avoid strong CYP3A4 inhibitors, such as clarithromycin and ketoconazole
- Avoid strong CYP3A4 inducers, such as rifampin and carbamazepine
- Grapefruit may raise lurasidone levels
- Alcohol and sedating medicines can increase sleepiness
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.