About lurasidone hci
Second-generation antipsychotic
Used for
- Schizophrenia in adults and adolescents
- Bipolar depression in adults and children
Usual adult dose
Schizophrenia: 40 mg once daily with food; bipolar depression: 20 mg once daily with food.
Usual dose in children
Schizophrenia, ages 13–17: 40 mg once daily with food. Bipolar depression, ages 10–17: 20 mg once daily with food.
Common side effects
- Nausea
- Sleepiness or restlessness
- Movement problems
- Weight gain
Important warnings
- Take with at least 350 calories of food.
- May cause abnormal movements, high blood sugar, or increased cholesterol.
- Can cause dizziness or fainting, especially when standing.
- Not approved for dementia-related psychosis; increased risk of death in older adults.
Pregnancy
May cause newborn movement or withdrawal symptoms when used during the third trimester.
Breastfeeding
Limited information; discuss potential infant exposure with a healthcare professional.
Interactions
- Avoid strong CYP3A4 inhibitors, such as ketoconazole and clarithromycin.
- Avoid strong CYP3A4 inducers, such as rifampin and carbamazepine.
- Grapefruit may increase lurasidone levels.
- Alcohol and sedatives can increase drowsiness.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.