About loncastuximab tesirine ipyi
CD19-directed antibody-drug conjugate
Used for
- Treats adults with relapsed or refractory large B-cell lymphoma after at least two prior systemic treatments.
Usual adult dose
0.15 mg/kg intravenously every 3 weeks for 2 cycles, then 0.075 mg/kg every 3 weeks.
Common side effects
- Low blood counts
- Swelling or fluid retention
- Nausea or fatigue
- Skin reactions and liver enzyme increases
Important warnings
- Can cause serious low blood counts and infections.
- Fluid retention, including around the heart or lungs, can be serious.
- May cause liver toxicity; blood tests are monitored.
- Avoid or use effective contraception during treatment and for 4 months afterward.
Pregnancy
May harm an unborn baby. Pregnancy status should be checked before treatment; effective contraception is recommended during treatment and for 4 months afterward.
Breastfeeding
Breastfeeding is not recommended during treatment or for 3 months after the final dose.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.