About lixisenatide
GLP-1 receptor agonist
Used for
- Alongside diet and exercise, treats type 2 diabetes in adults.
- Helps lower blood sugar and may support weight loss.
Usual adult dose
Start with 10 micrograms under the skin once daily for 14 days, then 20 micrograms once daily. Inject within one hour before the same meal each day.
Common side effects
- Nausea, vomiting, or diarrhoea
- Low blood sugar, especially with insulin or sulfonylureas
- Headache or dizziness
- Injection-site reactions
Important warnings
- Not for type 1 diabetes or diabetic ketoacidosis.
- Pancreatitis has been reported; severe persistent abdominal pain needs prompt assessment.
- May cause dehydration and kidney problems, particularly with vomiting or diarrhoea.
- Not recommended in severe kidney impairment; delayed stomach emptying can affect other medicines.
Pregnancy
Not recommended during pregnancy; blood sugar treatment should be reviewed with a clinician.
Breastfeeding
It is unknown whether lixisenatide passes into breast milk; use requires clinician review.
Interactions
- Insulin or sulfonylureas can increase low blood sugar risk.
- Slowed stomach emptying may alter absorption of oral medicines, including warfarin or antibiotics.
- Oral contraceptives may be less reliably absorbed; follow product guidance on timing.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.