About lixisenatid e
GLP-1 receptor agonist
Used for
- Alongside diet and exercise, treats type 2 diabetes in adults.
- Helps improve blood sugar control; not for treating type 1 diabetes.
Usual adult dose
Inject under the skin once daily, within an hour before the first meal. Usually start at 10 micrograms daily for 14 days, then 20 micrograms daily.
Common side effects
- Nausea, vomiting, or diarrhea
- Headache or dizziness
- Low blood sugar, especially with insulin or sulfonylureas
- Injection-site reactions
Important warnings
- Not for type 1 diabetes or diabetic ketoacidosis.
- Can cause pancreatitis; seek urgent care for severe, persistent abdominal pain.
- May cause dehydration and kidney problems, especially with vomiting or diarrhea.
- May delay stomach emptying; not recommended with severe gastroparesis.
Pregnancy
Not recommended during pregnancy; discuss alternatives with a healthcare professional.
Breastfeeding
It is unknown whether lixisenatide passes into breast milk; discuss use with a healthcare professional.
Interactions
- May affect absorption of medicines taken by mouth; especially relevant for medicines needing rapid absorption.
- Insulin or sulfonylureas increase low-blood-sugar risk; dose adjustment may be needed.
- Do not combine with another GLP-1 receptor agonist.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.