About live + non replicating smallpox + monkeypox vaccine
Live, non-replicating viral vaccine
Used for
- Prevention of smallpox in adults at risk of exposure.
- Prevention of mpox in adults at risk of exposure.
Usual adult dose
Two doses 28 days apart, given under the skin. For certain people, an authorized intradermal schedule may be used.
Common side effects
- Injection-site pain, redness, swelling, or itching
- Headache, muscle aches, tiredness, or nausea
- Fever or chills
- Rare severe allergic reactions
Important warnings
- Avoid vaccination after a severe allergic reaction to a previous dose or vaccine component.
- People with weakened immune systems may have reduced protection.
- Tell vaccination staff about severe allergies, heart problems, or prior smallpox vaccination.
- Not approved for routine use in children; use may be authorized during outbreaks.
Pregnancy
Human pregnancy data are limited. Use during pregnancy may be considered when exposure risk warrants vaccination.
Breastfeeding
It is not known whether vaccine components pass into breast milk; breastfeeding is not a reason to delay vaccination when indicated.
Interactions
- Immune-suppressing treatments may reduce the vaccine response.
- Other vaccines can generally be given at the same visit, at separate injection sites.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.