About lincomycin hydrochloride
Lincosamide antibiotic
Used for
- Treats serious infections caused by susceptible bacteria, especially when other antibiotics are unsuitable.
Usual adult dose
Usually 600 mg to 1 g intramuscularly every 24 hours; severe infections may require 1 g every 12 hours, given intravenously.
Usual dose in children
For children over one month: 10 mg/kg intramuscularly every 24 hours; severe infections may require 10 mg/kg every 12 hours.
Common side effects
- Diarrhoea, nausea, or abdominal pain
- Injection-site pain
- Rash or itching
- Severe antibiotic-associated colitis
Important warnings
- Can cause potentially severe or fatal diarrhoea from C. difficile infection, during treatment or afterward.
- Use only for susceptible bacterial infections; it does not treat viral illnesses.
- Intravenous doses must be diluted and infused slowly; rapid administration can cause serious heart or blood-pressure effects.
- Avoid with a history of lincomycin- or clindamycin-associated colitis.
Pregnancy
Use only when clearly needed; human pregnancy safety data are limited.
Breastfeeding
Lincomycin may enter breast milk. Consider infant diarrhoea, thrush, or rash; seek clinical guidance.
Interactions
- Erythromycin may oppose lincomycin’s antibacterial action.
- May enhance effects of neuromuscular-blocking medicines.
- Tell clinicians about other antibiotics and medicines, especially those affecting muscle relaxation.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.