About levosulpiride
Benzamide dopamine D2 receptor antagonist
Used for
- Short-term treatment of indigestion and reflux symptoms in some countries
- Treatment of nausea and vomiting in some countries
Usual adult dose
Often 25 mg three times daily before meals; dosing varies by country and indication.
Common side effects
- Sleepiness or dizziness
- Raised prolactin, causing breast changes or menstrual problems
- Tremor, stiffness, or other movement problems
- Diarrhea or constipation
Important warnings
- May cause serious abnormal movements, especially with prolonged use.
- Avoid with epilepsy, gastrointestinal bleeding or blockage, or pheochromocytoma.
- Use caution with heart rhythm problems, older age, or kidney impairment.
- Availability and approved uses differ by country.
Pregnancy
Avoid unless a clinician determines it is necessary; pregnancy safety evidence is limited.
Breastfeeding
Generally avoid; it may increase prolactin and affect milk production. Safety evidence is limited.
Interactions
- Levodopa and dopamine agonists can oppose its effects.
- Sedatives and alcohol may increase drowsiness.
- Medicines that prolong QT interval may increase heart rhythm risk.
- Antacids or sucralfate can reduce absorption; separate doses.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.