About lenograstim
Granulocyte colony-stimulating factor
Used for
- Reduces infection risk after chemotherapy by increasing white blood cells.
- Helps white blood cell recovery after bone marrow or stem-cell transplant.
- Mobilizes stem cells for collection before transplantation.
Usual adult dose
Usually 150 micrograms/m² daily by injection after chemotherapy or transplant; collection regimens vary.
Usual dose in children
Usually 150 micrograms/m² daily by injection after chemotherapy or transplant; specialist-directed dosing varies by indication.
Common side effects
- Bone or muscle pain
- Headache
- Injection-site reactions
- Nausea
Important warnings
- Rarely causes serious spleen enlargement or rupture; left upper abdominal or shoulder pain needs urgent assessment.
- Rarely causes severe allergic reactions or breathing problems.
- Blood counts and spleen-related symptoms may require monitoring.
- Use cautiously with sickle cell disease or serious lung problems.
Pregnancy
Limited information; use only when clearly needed after weighing potential benefits and risks.
Breastfeeding
It is not known whether lenograstim passes into breast milk; breastfeeding decisions require clinical assessment.
Interactions
- Lithium may increase white blood cell production; monitoring may be needed.
- Chemotherapy medicines can affect blood counts; treatment timing should be coordinated.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.