About lemborexant
Dual orexin receptor antagonist
Used for
- Treatment of insomnia involving difficulty falling asleep or staying asleep.
Usual adult dose
5 mg once nightly; may increase to 10 mg if needed and tolerated.
Common side effects
- Sleepiness or fatigue
- Headache
- Dizziness
- Abnormal dreams or sleep paralysis
Important warnings
- Take only when at least seven hours remain for sleep.
- Avoid alcohol; it can worsen drowsiness and impairment.
- May cause next-day impairment; avoid driving if affected.
- Rarely, unusual sleep behaviors or temporary inability to move may occur.
Pregnancy
Limited information; use during pregnancy only when clinically necessary.
Breastfeeding
Unknown whether it passes into breast milk; effects on infants are uncertain.
Interactions
- Strong CYP3A inhibitors can increase levels; avoid combination.
- Strong or moderate CYP3A inducers can reduce effectiveness; avoid combination.
- Other sedatives, including opioids, can increase drowsiness and impairment.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.