About lecanamab
Anti-amyloid monoclonal antibody
Used for
- Treats early Alzheimer’s disease, including mild cognitive impairment or mild dementia, with confirmed amyloid plaques.
Usual adult dose
10 mg/kg by intravenous infusion every two weeks.
Common side effects
- Infusion-related reactions, including fever, chills, nausea, or headache
- Amyloid-related brain swelling or bleeding (ARIA)
- Headache
- Falls
Important warnings
- ARIA can cause serious brain swelling or bleeding; monitoring with brain MRI is required.
- Risk of ARIA is higher in people with two copies of the APOE ε4 gene.
- Use caution with blood thinners or medicines that increase bleeding risk.
- Treatment is intended for early Alzheimer’s disease with confirmed amyloid plaques.
Pregnancy
Human pregnancy data are insufficient; potential fetal risk is unknown.
Breastfeeding
It is unknown whether lecanemab passes into breast milk or affects a breastfed infant.
Interactions
- Blood thinners and clot-dissolving medicines may increase concern about brain bleeding.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.