About laropiprant + nicotinic acid
Nicotinic acid and prostaglandin D2 antagonist
Used for
- Used with diet and other lipid-lowering treatment for abnormal cholesterol and triglycerides.
Usual adult dose
Usually one tablet daily initially, increased gradually to two tablets twice daily with food.
Common side effects
- Flushing, warmth, itching, or tingling
- Headache or dizziness
- Nausea, diarrhea, or indigestion
- Raised liver enzymes or blood sugar
Important warnings
- Not for active liver disease or unexplained persistent liver-test abnormalities.
- Can cause liver injury; liver tests require monitoring.
- May worsen gout, diabetes, or peptic-ulcer disease.
- Avoid alcohol and hot drinks around dosing; they can worsen flushing.
Pregnancy
Not recommended during pregnancy; lipid treatment is generally unnecessary, and safety is not established.
Breastfeeding
Avoid during breastfeeding; safety is not established and treatment may affect the infant.
Interactions
- Statins may increase muscle-injury risk.
- Blood-pressure medicines may increase dizziness or low blood pressure.
- Anticoagulants may require closer monitoring.
- Bile-acid sequestrants can reduce absorption; separate dosing.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.