About dolutegravir + lamivudine
Integrase inhibitor and nucleoside reverse transcriptase inhibitor
Used for
- Treats HIV-1 infection with other appropriate HIV medicines or as a complete two-drug regimen in selected adults.
Usual adult dose
One tablet by mouth once daily for adults who meet eligibility criteria.
Common side effects
- Headache
- Nausea
- Diarrhea
- Insomnia
Important warnings
- Not suitable for some people with hepatitis B or certain drug resistance.
- May cause serious liver problems; liver monitoring may be needed.
- Rarely, severe allergic reactions or muscle breakdown occur.
- Do not stop or change treatment without clinical guidance.
Pregnancy
Use during pregnancy only after considering benefits and risks; HIV treatment should not be interrupted.
Breastfeeding
People with HIV are generally advised not to breastfeed because of HIV transmission risk.
Interactions
- Dofetilide is contraindicated.
- Rifampin, carbamazepine, and some other seizure medicines can reduce dolutegravir levels.
- Antacids or supplements containing calcium, iron, magnesium, or aluminum can interfere with absorption.
- Trimethoprim, metformin, and certain HIV medicines may require review or monitoring.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.