About l uste kinum ab
Interleukin-12/23 monoclonal antibody
Used for
- Moderate to severe Crohn’s disease in adults
- Moderately to severely active ulcerative colitis in adults
Usual adult dose
Crohn’s disease or ulcerative colitis: one weight-based intravenous infusion, approximately 6 mg/kg, followed by subcutaneous maintenance dosing.
Common side effects
- Infections, including upper respiratory infections
- Headache
- Tiredness
- Infusion reactions
Important warnings
- Serious infections can occur; tuberculosis screening is recommended before treatment.
- Avoid live vaccines during treatment.
- Do not start during a serious active infection.
- Rarely, severe allergic reactions can occur.
Pregnancy
Limited human data; use during pregnancy only when clinically needed. Discuss risks and benefits with a healthcare professional.
Breastfeeding
It is unknown whether ustekinumab passes into human milk; consider treatment benefits and potential infant risks.
Interactions
- Live vaccines may cause infection and should be avoided.
- Other biologic immunosuppressants may increase infection risk; combined use is generally avoided.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.