About l baric itinib
Janus kinase (JAK) inhibitor
Used for
- Rheumatoid arthritis
- Atopic dermatitis
- Alopecia areata
- Hospitalized adults with COVID-19 requiring oxygen
Usual adult dose
Usually 2–4 mg once daily for rheumatoid arthritis; 4 mg once daily for atopic dermatitis or alopecia areata. COVID-19: 4 mg once daily, usually up to 14 days.
Usual dose in children
Atopic dermatitis, ages 2 years and older: usually 2 mg once daily; may increase to 4 mg based on response and weight.
Common side effects
- Upper respiratory infections
- Nausea
- Headache
- Shingles or other serious infections
Important warnings
- May increase risk of serious infections, blood clots, cancer, and major heart problems.
- Check blood counts, liver tests, and cholesterol during treatment.
- Avoid live vaccines; screen for tuberculosis and viral hepatitis before treatment.
- Dose adjustments may be needed for kidney problems or interacting medicines.
Pregnancy
May harm an unborn baby; avoid use during pregnancy. Effective contraception is advised during treatment and for one week afterward.
Breastfeeding
Avoid breastfeeding during treatment and for one week after the last dose.
Interactions
- Probenecid can increase baricitinib exposure; dose reduction may be needed.
- Other strong immunosuppressants can increase infection risk.
- Live vaccines may be unsafe during treatment.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.