About khellin + methenamine + piperazine
Urinary antiseptic and antispasmodic combination
Used for
- Traditionally used for urinary discomfort and bladder spasms; evidence and approved uses vary by country.
Common side effects
- Nausea or stomach upset
- Headache or dizziness
- Allergic reactions
Important warnings
- Methenamine may not work well in alkaline urine.
- Avoid with severe kidney or liver disease, or severe dehydration.
- Piperazine can cause neurological effects, especially with kidney impairment.
- Khellin may increase sensitivity to sunlight.
Pregnancy
Safety is not established; use during pregnancy depends on local product guidance.
Breastfeeding
Safety is not established; local product guidance should be followed.
Interactions
- Sulfonamide antibiotics may interact with methenamine.
- Urine-alkalinizing products can reduce methenamine effectiveness.
- Other medicines that affect the nervous system may increase piperazine-related effects.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.