About isotretinoin cap
Oral retinoid for severe acne
Used for
- Severe acne that has not responded to other treatments
Usual adult dose
Usually 0.5–1 mg/kg daily, adjusted by a specialist; treatment commonly lasts 16–24 weeks.
Usual dose in children
Not routinely used before puberty; specialist dosing may be considered for adolescents with severe acne.
Common side effects
- Very dry lips, skin, eyes, and nose
- Nosebleeds
- Muscle or joint aches
- Raised liver enzymes or blood fats
Important warnings
- Can cause severe birth defects; pregnancy must be avoided during treatment and for one month afterward.
- Requires strict pregnancy-prevention measures and monitoring where pregnancy is possible.
- Do not donate blood during treatment or for one month afterward.
- Seek urgent care for severe mood changes, severe headache, or vision changes.
Pregnancy
Must not be used during pregnancy; it causes serious birth defects. Pregnancy-prevention requirements apply.
Breastfeeding
Avoid during treatment; it is not recommended while breastfeeding.
Interactions
- Vitamin A supplements may increase toxic effects.
- Tetracycline antibiotics may increase pressure around the brain; avoid combining.
- Other acne treatments that dry or irritate skin can worsen irritation.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.