About isosorbide dinitrate
Organic nitrate antianginal vasodilator
Used for
- Prevention and treatment of angina (chest pain)
- Sometimes used for heart failure with other medicines
Usual adult dose
Angina: typically 5–20 mg under the tongue; repeat every 5–10 minutes, up to three doses.
Common side effects
- Headache
- Dizziness or light-headedness
- Flushing
- Low blood pressure
Important warnings
- Can cause fainting or a dangerous drop in blood pressure.
- Do not combine with sildenafil, tadalafil, vardenafil, or riociguat.
- Seek emergency care for chest pain that persists after prescribed doses.
- Regular use may reduce effectiveness; follow the prescribed schedule.
Pregnancy
Use only when clearly needed; pregnancy safety information is limited.
Breastfeeding
Information is limited; use only with professional guidance.
Interactions
- Sildenafil, tadalafil, vardenafil, and riociguat can cause severe low blood pressure.
- Alcohol and blood-pressure medicines may increase dizziness or low blood pressure.
- Other nitrates can intensify effects and side effects.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.