About indometha cin
Nonsteroidal anti-inflammatory drug (NSAID)
Used for
- Pain and inflammation from arthritis
- Acute gout attacks
- Painful shoulder inflammation
- Muscle and joint pain
Usual adult dose
Usually 25 mg two or three times daily; dosing depends on the condition and prescription.
Common side effects
- Nausea, indigestion, or stomach pain
- Diarrhea or constipation
- Headache or dizziness
- Swelling or raised blood pressure
Important warnings
- Can cause stomach ulcers, bleeding, or perforation.
- May increase risks of heart attack and stroke.
- Avoid with active stomach bleeding or severe kidney, liver, or heart failure.
- Use the lowest effective dose for the shortest time.
Pregnancy
Avoid from 20 weeks unless specifically directed; avoid from 30 weeks because of fetal risks.
Breastfeeding
Small amounts enter milk; short-term use may be compatible, but alternatives are often preferred.
Interactions
- Blood thinners and antiplatelet medicines increase bleeding risk.
- Other NSAIDs, including ibuprofen and naproxen, increase side effects.
- ACE inhibitors, ARBs, and diuretics may worsen kidney function.
- Lithium and methotrexate levels may rise.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.