About imipenem
Carbapenem antibiotic
Used for
- Serious bacterial infections, including hospital-acquired infections
- Infections caused by susceptible bacteria when other antibiotics are unsuitable
Usual adult dose
Usually 500 mg intravenously every 6 hours; dose depends on infection and kidney function.
Usual dose in children
Children aged 3 months and older: usually 15–25 mg/kg intravenously every 6 hours; specialist dosing is required.
Common side effects
- Nausea, vomiting, or diarrhea
- Rash or allergic reactions
- Infusion-site pain or inflammation
- Seizures, especially with kidney impairment or excessive doses
Important warnings
- Use only for bacterial infections; it does not treat viral illnesses.
- Dose adjustment is needed with impaired kidney function.
- Tell clinicians about penicillin or cephalosporin allergy and seizure history.
- Not suitable for meningitis; serious allergic reactions require urgent care.
Pregnancy
Use only when clearly needed; a clinician should weigh potential benefits and risks.
Breastfeeding
Small amounts may enter milk; monitor the infant for diarrhea or thrush.
Interactions
- Valproate or divalproex levels can fall, increasing seizure risk.
- Ganciclovir may increase seizure risk.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.