About idursulfase
Enzyme replacement therapy
Used for
- Long-term treatment of Hunter syndrome (mucopolysaccharidosis II).
Usual adult dose
0.5 mg/kg by intravenous infusion once weekly.
Usual dose in children
0.5 mg/kg by intravenous infusion once weekly; used in children.
Common side effects
- Infusion reactions, including fever, headache, rash, or flushing
- Hives or itching
- High blood pressure
- Injection-site reactions
Important warnings
- Serious allergic reactions, including anaphylaxis, can occur during or after infusion.
- People with severe airway or lung disease may have greater risk of serious infusion reactions.
- Antibodies to idursulfase may develop and affect treatment response.
- Infusions require monitoring by healthcare professionals.
Pregnancy
Human pregnancy data are limited; use only when the potential benefit justifies possible fetal risk.
Breastfeeding
It is unknown whether idursulfase passes into breast milk; weigh treatment benefits against potential risks.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.