About hypericum perforatum extract
Herbal antidepressant
Used for
- Traditionally used for mild to moderate depressive symptoms
Usual adult dose
Commonly, 300 mg of extract three times daily; products vary in extract strength and standardization.
Common side effects
- Stomach upset
- Dry mouth
- Dizziness
- Increased sensitivity to sunlight
Important warnings
- Can cause serious interactions with many medicines.
- May worsen mania in people with bipolar disorder.
- Avoid combining with other antidepressants unless supervised.
- May reduce effectiveness of hormonal contraceptives and other medicines.
Pregnancy
Safety is uncertain; generally avoided during pregnancy.
Breastfeeding
Safety is uncertain; generally avoided during breastfeeding.
Interactions
- Can reduce effects of birth control pills, transplant medicines, anticoagulants, and HIV medicines.
- Combining with antidepressants or migraine medicines can cause serotonin toxicity.
- Can interact with many other medicines; effects may persist after stopping.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.