About hydroxych loroquine sulfate
Antimalarial and disease-modifying antirheumatic drug
Used for
- Prevention and treatment of malaria caused by susceptible parasites
- Rheumatoid arthritis
- Lupus, including systemic and discoid lupus
Usual adult dose
For rheumatoid arthritis or lupus: usually 200–400 mg once daily. Malaria dosing varies by purpose and region.
Usual dose in children
For malaria only: dose is based on body weight; maximum 6.5 mg/kg of hydroxychloroquine base per dose.
Common side effects
- Nausea, stomach pain, or diarrhea
- Headache or dizziness
- Rash or itching
- Blurred vision or other eye problems
Important warnings
- Long-term use can damage the retina; eye examinations are needed.
- Risk of heart rhythm problems, especially with heart disease or interacting medicines.
- Can lower blood sugar and cause severe low blood sugar.
- Use only for malaria strains known to be susceptible; resistance occurs.
Pregnancy
May be used during pregnancy for lupus or malaria when clinically needed; stopping lupus treatment may cause harm.
Breastfeeding
Small amounts enter breast milk; use is generally considered compatible, including with usual doses.
Interactions
- Medicines that prolong heart rhythm, such as some antibiotics or antiarrhythmics
- Digoxin, which may reach higher blood levels
- Antacids can reduce absorption; separate by at least four hours
- Tamoxifen may increase the risk of retinal damage
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.