About hydrocortisone
Corticosteroid (glucocorticoid)
Used for
- Severe allergic reactions and asthma attacks
- Adrenal crisis or severe cortisol deficiency
- Severe inflammation when oral treatment is unsuitable
Usual adult dose
For adrenal crisis, 100 mg by injection, then usually 200 mg over 24 hours; other doses depend on condition.
Usual dose in children
For adrenal crisis, commonly 50 mg/m² by injection, followed by ongoing treatment; specialist dosing varies.
Common side effects
- Raised blood sugar
- Fluid retention and higher blood pressure
- Mood or sleep changes
- Increased infection risk
Important warnings
- Emergency treatment should not be delayed in adrenal crisis.
- Longer treatment can suppress natural adrenal hormone production.
- May mask infection or worsen some infections.
- Repeated or prolonged use can affect bones, eyes, and growth.
Pregnancy
May be used when needed; clinicians weigh benefits and risks, especially with prolonged treatment.
Breastfeeding
Usually compatible with breastfeeding; prolonged or high-dose treatment may require monitoring.
Interactions
- Blood thinners, including warfarin
- Diabetes medicines
- Some antifungals and antibiotics
- Vaccines, especially live vaccines
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.