About hydrochlorothiazide + trimetrene
Thiazide diuretic and potassium-sparing diuretic
Used for
- Treats high blood pressure
- Reduces fluid swelling (edema), including from heart failure
Usual adult dose
Usually one tablet once daily; dose depends on response and product formulation.
Common side effects
- Dizziness or lightheadedness
- Nausea or stomach upset
- Changes in blood potassium or sodium
- Increased urination
Important warnings
- Can cause high potassium, especially with kidney disease or diabetes.
- Kidney function and blood electrolytes may need monitoring.
- Avoid potassium supplements and salt substitutes containing potassium unless prescribed.
- May cause dehydration, low blood pressure, or worsening kidney problems.
Pregnancy
Use only when clearly needed; hydrochlorothiazide is generally avoided for routine pregnancy-related swelling or high blood pressure.
Breastfeeding
Hydrochlorothiazide may reduce milk supply, especially at higher doses; seek medical guidance about use.
Interactions
- ACE inhibitors or ARBs can increase potassium.
- Potassium supplements or potassium-containing salt substitutes can cause dangerously high potassium.
- Lithium levels may rise.
- NSAIDs, such as ibuprofen, may reduce diuretic effects and affect kidney function.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.