About irbesartan + hydrochlorothiazide
Angiotensin receptor blocker and thiazide diuretic
Used for
- Treats high blood pressure when one medicine alone is insufficient.
Usual adult dose
Usually one tablet once daily; the prescriber may adjust the dose.
Common side effects
- Dizziness or light-headedness
- Low blood pressure
- Changes in kidney function or blood potassium
- Nausea or fatigue
Important warnings
- Can cause dehydration, low blood pressure, or kidney problems.
- May raise potassium or lower sodium; blood tests may be needed.
- Avoid during pregnancy; it can seriously harm an unborn baby.
- Use caution with kidney or liver disease, gout, or lupus.
Pregnancy
Not recommended; medicines affecting the renin–angiotensin system can harm or cause death to the developing baby, especially later in pregnancy.
Breastfeeding
Use is generally not recommended, particularly for newborn or premature infants; alternatives may be preferred.
Interactions
- NSAID painkillers, including ibuprofen, may worsen kidney function or reduce blood pressure control.
- Potassium supplements or potassium-sparing medicines can raise potassium levels.
- Lithium levels may rise and become toxic.
- Other blood-pressure medicines or diuretics can increase dizziness or low blood pressure.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.