About hydrochlo rothiazide
Thiazide diuretic
Used for
- High blood pressure
- Fluid retention (oedema)
Usual adult dose
Usually 12.5–25 mg once daily for high blood pressure; 25–100 mg daily for fluid retention, sometimes divided.
Usual dose in children
For fluid retention, usually 1–2 mg/kg daily, up to 37.5 mg for ages 2–12; dosing is specialist-directed.
Common side effects
- Frequent urination
- Dizziness, especially when standing
- Low sodium or potassium
- Increased uric acid or blood sugar
Important warnings
- May cause dehydration or low blood pressure.
- Kidney function and blood salts may need monitoring.
- Use caution with gout, diabetes, or kidney or liver disease.
- Seek urgent care for severe rash, facial swelling, or difficulty breathing.
Pregnancy
May affect blood volume and placental blood flow; generally avoided for routine high blood pressure during pregnancy.
Breastfeeding
May reduce milk supply, particularly at higher doses; discuss suitability with a healthcare professional.
Interactions
- Lithium: can increase lithium levels.
- NSAIDs, such as ibuprofen: may reduce its effect and affect kidney function.
- Digoxin: low potassium can increase toxicity risk.
- Other blood-pressure medicines: may increase dizziness or low blood pressure.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.