About human protein c
Plasma-derived protein C replacement
Used for
- Treatment and prevention of severe congenital protein C deficiency.
- Short-term prevention and treatment of skin and blood-clot complications in affected patients.
Usual adult dose
Dose is individualized by weight, protein C levels, and clinical response; given by intravenous injection.
Usual dose in children
Used in children, including newborns; dose is individualized by weight, protein C levels, and clinical response.
Common side effects
- Allergic reactions, including severe hypersensitivity.
- Dizziness, rash, itching, or injection-site reactions.
- Fever or headache.
- Bleeding, particularly when combined with anticoagulants.
Important warnings
- Administer intravenously under medical supervision; monitor protein C activity and clotting.
- Severe allergic reactions can occur, especially in people with protein C inhibitors.
- Contains trace heparin; avoid in heparin-induced thrombocytopenia.
- Human plasma products carry a residual risk of transmitting infections.
Pregnancy
Use only when clearly needed; experience is limited, and untreated protein C deficiency can pose serious risks.
Breastfeeding
There is limited information; use requires consideration of maternal need and potential risks.
Interactions
- Anticoagulants, including warfarin, can increase bleeding risk; careful monitoring is needed.
- Other medicines affecting clotting may alter bleeding or clotting risk.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.