About human immunoglobulin anti d rh factor
Human anti-D immunoglobulin
Used for
- Prevents RhD sensitisation in RhD-negative pregnant people
- Treats immune thrombocytopenia in selected RhD-positive patients
Usual adult dose
Pregnancy prevention: 1,500 IU around 28–30 weeks, or doses according to local protocols. After birth or a sensitising event, dose depends on exposure and fetal-cell testing.
Usual dose in children
Immune thrombocytopenia: 50–75 micrograms/kg (250–375 IU/kg) intravenously as a single dose; specialist-directed.
Common side effects
- Injection-site pain or tenderness
- Headache, fever, or chills
- Nausea or rash
- Rarely, severe allergic reaction or haemolysis
Important warnings
- For RhD-negative people who have not already formed anti-D antibodies
- Intramuscular or intravenous use depends on the indication and product instructions
- Can interfere with some blood tests
- Immune thrombocytopenia treatment can cause serious haemolysis
Pregnancy
Used during pregnancy and after birth to prevent RhD sensitisation when indicated.
Breastfeeding
Generally compatible with breastfeeding.
Interactions
- May reduce responses to live vaccines, including measles, mumps, rubella, and varicella vaccines
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.