About human fibrinogen + human thrombin
Topical fibrin sealant
Used for
- Helps control bleeding during surgery when standard methods are ineffective or impractical.
- Seals tissue and supports healing after surgery.
Usual adult dose
Applied by a surgeon directly to the bleeding or leaking tissue; amount depends on the area treated.
Usual dose in children
Applied by a surgeon; amount depends on the area treated.
Common side effects
- Fever
- Nausea
- Clots in blood vessels
- Allergic reactions, rarely severe
Important warnings
- For use on tissue surfaces only; do not inject into blood vessels.
- Avoid use in people with serious allergy to human blood products or product components.
- Human plasma products carry a residual risk of infection transmission.
- May cause blood clots if it enters blood vessels.
Pregnancy
Use only when clearly needed; pregnancy safety data are limited.
Breastfeeding
Breastfeeding safety data are limited; use only when clinically necessary.
Interactions
- No important medicine interactions are established; topical use may be affected by clot-dissolving agents.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.