About human fibrinogen
Human plasma-derived fibrinogen concentrate
Used for
- Treats bleeding in congenital fibrinogen deficiency, including afibrinogenemia and hypofibrinogenemia.
- Treats bleeding in acquired fibrinogen deficiency, such as during major surgery or trauma.
Usual adult dose
Intravenous dose is based on body weight, measured fibrinogen level, and bleeding severity; repeat doses may be needed.
Usual dose in children
Used in children; intravenous dose is calculated from body weight and fibrinogen levels.
Common side effects
- Allergic reactions, including rash, itching, or difficulty breathing
- Blood clots
- Fever or chills
- Nausea or vomiting
Important warnings
- Risk of blood clots, especially with high fibrinogen levels or other clotting risks.
- Severe allergic reactions can occur.
- Plasma-derived product: residual risk of transmitting infections remains.
- Monitor fibrinogen levels and clinical response during treatment.
Pregnancy
Use only when clearly needed; pregnancy-specific safety information is limited.
Breastfeeding
Safety information is limited; use requires consideration of clinical need.
Interactions
- No specific medicine interactions are well established.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.