About human fibrinogen
Human fibrinogen replacement product
Used for
- Treats or prevents bleeding in congenital fibrinogen deficiency.
- Treats acquired fibrinogen deficiency with serious bleeding, depending on local approval.
Usual adult dose
Individualized by weight, fibrinogen level, and bleeding; commonly 30–70 mg/kg intravenously for congenital deficiency.
Usual dose in children
Individualized by weight and fibrinogen level; commonly 30–70 mg/kg intravenously for congenital deficiency.
Common side effects
- Headache
- Fever or chills
- Nausea
- Blood clots
Important warnings
- Can cause serious blood clots, including in people without known clotting risks.
- Severe allergic reactions are possible.
- Use only after measuring fibrinogen and under specialist supervision.
- Plasma-derived product; residual risk of transmitting infection cannot be completely excluded.
Pregnancy
Use only when clearly needed; pregnancy increases clot risk, and evidence is limited.
Breastfeeding
Evidence is limited; use when clinically necessary after weighing benefits and risks.
Interactions
- No specific drug interactions are established; medicines affecting clotting may alter overall risk.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.