About human anti d
Human anti-D immunoglobulin
Used for
- Prevents RhD sensitisation in RhD-negative people exposed to RhD-positive blood.
- Prevents RhD sensitisation during pregnancy and after delivery when indicated.
- Treats immune thrombocytopenia in selected RhD-positive patients.
Usual adult dose
Prevention: usually 300 micrograms (1,500 IU), with timing based on exposure or pregnancy protocol. Immune thrombocytopenia dosing is specialist-directed.
Usual dose in children
For eligible children with immune thrombocytopenia, dose is based on body weight and specialist protocols; not used routinely for children.
Common side effects
- Injection-site pain or swelling
- Headache, fever, or chills
- Nausea or feeling unwell
- Rare severe allergic reaction or haemolysis
Important warnings
- Must be given by injection into a muscle or vein as directed.
- Can cause red blood cell destruction, especially when used for immune thrombocytopenia.
- Seek urgent care for breathing difficulty, facial swelling, dark urine, or jaundice.
- Vaccination response to some live vaccines may be reduced temporarily.
Pregnancy
Used during pregnancy and after delivery when indicated to prevent RhD sensitisation; it does not treat an already sensitised person.
Breastfeeding
Generally compatible with breastfeeding; clinically significant effects in breastfed infants are not expected.
Interactions
- May reduce responses to live vaccines, such as measles, mumps, rubella, and varicella vaccines.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.