About human a von willebrand factor
Plasma-derived von Willebrand factor
Used for
- Prevention and treatment of bleeding in von Willebrand disease.
- Perioperative bleeding prevention when other treatments are unsuitable.
Usual adult dose
Individualised by weight, von Willebrand factor levels, bleeding severity, and procedure; specialist-directed.
Usual dose in children
Individualised by weight and clinical response; specialist-directed when indicated.
Common side effects
- Headache
- Infusion reactions, including fever or chills
- Blood clots
- Development of antibodies against von Willebrand factor
Important warnings
- Can cause blood clots, especially with high factor levels or other risk factors.
- Monitor factor levels during repeated doses and major surgery.
- Severe allergic reactions can occur.
- Made from human plasma; a residual infection risk cannot be completely excluded.
Pregnancy
Use only when clearly needed; experience is limited. Specialist assessment is required.
Breastfeeding
Use only when clearly needed; effects are not well studied. Specialist assessment is required.
Interactions
- No specific drug interactions are established; medicines affecting clotting may alter bleeding or clot risk.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.