About herbal johns wort dry extract
Herbal antidepressant (St John’s wort)
Used for
- Traditionally used for mild to moderate depressive symptoms.
Usual adult dose
Varies by extract and product; follow the specific product label. Doses are not interchangeable between extracts.
Common side effects
- Stomach upset or diarrhea
- Dizziness or tiredness
- Increased sensitivity to sunlight
- Restlessness or sleep problems
Important warnings
- Can cause serious interactions by reducing levels of many medicines.
- Avoid combining with antidepressants or other serotonin-raising medicines; serotonin toxicity may occur.
- May worsen severe depression or trigger mania in people with bipolar disorder.
- Sun protection may be needed, especially with prolonged use.
Pregnancy
Avoid use unless a clinician recommends it; safety is not well established.
Breastfeeding
Safety is uncertain; use only with professional guidance.
Interactions
- Can reduce effectiveness of hormonal contraceptives, transplant medicines, HIV medicines, anticoagulants, and many others.
- Combining with antidepressants, tramadol, or other serotonin-raising medicines can cause serotonin toxicity.
- May interact with seizure medicines, cancer treatments, and heart medicines.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.