About hepatitits b immunoglobulin
Hepatitis B immune globulin
Used for
- Prevents hepatitis B after exposure to infected blood
- Protects newborns whose mothers have hepatitis B
- Prevents hepatitis B recurrence after liver transplantation
Usual adult dose
After exposure: commonly 8–12 international units/kg intramuscularly, preferably within 24 hours. Exact dosing depends on the product and indication.
Usual dose in children
Exposed newborns: product-specific intramuscular dose within 12 hours of birth, with hepatitis B vaccine given at a separate injection site.
Common side effects
- Injection-site pain, redness, or swelling
- Headache
- Fever
- Rare severe allergic reactions
Important warnings
- Provides temporary protection; it is not a vaccine
- Does not treat established hepatitis B infection
- Severe allergic reactions possible, especially with certain IgA deficiencies
- Injection route depends on the specific product
Pregnancy
May be used during pregnancy when indicated to prevent hepatitis B after exposure.
Breastfeeding
Generally considered compatible with breastfeeding when indicated.
Interactions
- May reduce effectiveness of live vaccines, including measles and chickenpox
- Hepatitis B vaccine must be injected at a separate site
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.