About hepatitis b immunoglobulin
Hepatitis B immune globulin
Used for
- Prevents hepatitis B infection after exposure, including needlestick injuries or sexual contact.
- Protects newborns whose mothers have hepatitis B, alongside hepatitis B vaccination.
- Provides temporary protection for people at risk, such as liver transplant recipients.
Usual adult dose
Dose depends on exposure and product instructions; commonly 0.06 mL/kg by injection after exposure, with vaccine when indicated.
Usual dose in children
Newborns of hepatitis B-positive mothers: 0.5 mL by injection promptly after birth, alongside hepatitis B vaccine. Other doses depend on age and exposure.
Common side effects
- Injection-site pain, redness, or swelling
- Headache or tiredness
- Nausea
- Rare severe allergic reaction
Important warnings
- Give as soon as possible after exposure; protection is temporary.
- Does not treat established hepatitis B infection.
- Use separate injection sites from hepatitis B vaccine.
- Tell clinicians about previous immune globulin reactions or IgA deficiency.
Pregnancy
May be used when needed to prevent hepatitis B; benefits and risks depend on exposure.
Breastfeeding
Generally compatible with breastfeeding; preventing maternal infection may also protect the infant.
Interactions
- May reduce responses to live vaccines, including measles, mumps, rubella, and varicella; timing may need adjustment.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.