About hepatitis b immunoglobulin
Human hepatitis B immunoglobulin
Used for
- Provides short-term protection after hepatitis B exposure
- Prevents infection in newborns of mothers with hepatitis B
- Provides protection for certain people after liver transplantation
Usual adult dose
After exposure: commonly 0.06 mL/kg intramuscularly, as soon as possible; dosing varies by situation.
Usual dose in children
Newborns: commonly 0.5 mL intramuscularly after birth; other children receive weight-based doses.
Common side effects
- Injection-site pain or tenderness
- Headache
- Fever or chills
- Rare severe allergic reaction
Important warnings
- Not a substitute for hepatitis B vaccination when vaccination is indicated
- Use caution with previous severe reactions to human immunoglobulin
- Intramuscular injection may be unsuitable with bleeding disorders
- May interfere with some live-virus vaccines
Pregnancy
May be used when needed; clinical circumstances determine use.
Breastfeeding
Generally compatible; immunoglobulin is a normal component of breast milk.
Interactions
- May reduce responses to measles, mumps, rubella, or varicella vaccines; timing may need adjustment.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.