About guanfacine hydrochloride
Alpha-2A adrenergic receptor agonist
Used for
- Treats attention-deficit/hyperactivity disorder (ADHD), alone or with stimulant medicines.
Usual adult dose
Usually start at 1 mg once daily; increase by no more than 1 mg weekly, up to 7 mg daily.
Usual dose in children
For ages 6–17: start at 1 mg once daily; increase by no more than 1 mg weekly, up to 4 mg daily.
Common side effects
- Sleepiness or fatigue
- Low blood pressure or dizziness
- Slow heart rate
- Dry mouth or constipation
Important warnings
- Can cause fainting, low blood pressure, or slow heart rate.
- Do not stop suddenly; gradual dose reduction helps prevent rebound high blood pressure.
- Swallow tablets whole; do not crush, chew, or break.
- Avoid driving until effects on alertness are known.
Pregnancy
Human pregnancy data are limited; use requires weighing potential benefits against possible risks.
Breastfeeding
Information is limited; discuss potential infant effects and monitoring with a healthcare professional.
Interactions
- Medicines that cause sleepiness can increase sedation.
- Blood-pressure-lowering medicines can increase low blood pressure.
- Strong CYP3A4 inhibitors may raise guanfacine levels.
- Strong CYP3A4 inducers may lower guanfacine levels.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.