About granisetr on hydrochlo
Serotonin 5-HT3 receptor blocker
Used for
- Prevention and treatment of nausea and vomiting caused by chemotherapy
- Prevention and treatment of nausea and vomiting after surgery
Usual adult dose
Chemotherapy: usually 1 mg intravenously before treatment; dosing varies by regimen. Post-surgery: usually 1 mg intravenously.
Usual dose in children
Chemotherapy: children aged 2 years and older usually receive 10 micrograms/kg intravenously before treatment; limits vary by regimen.
Common side effects
- Headache
- Constipation or diarrhea
- Dizziness
- Raised liver enzyme levels
Important warnings
- May affect heart rhythm, especially with heart conditions or electrolyte imbalance.
- Use cautiously with medicines that prolong the QT interval.
- Serotonin syndrome is possible with other serotonergic medicines.
- May mask signs of reduced bowel movement.
Pregnancy
Human pregnancy information is limited; use only when a clinician considers it necessary.
Breastfeeding
It is unknown whether granisetron passes into breast milk; seek clinical guidance before use.
Interactions
- Other medicines that prolong the QT interval
- Serotonergic medicines, including some antidepressants
- Medicines affecting liver enzymes may alter granisetron exposure
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.