About glecaprevir + pibrentasvir
Direct-acting antiviral combination
Used for
- Treats chronic hepatitis C virus infection in adults and children aged 3 years and older.
Usual adult dose
Three tablets once daily with food, usually for 8 weeks; duration varies by treatment history and liver status.
Usual dose in children
For children aged 3 years and older, dose is based on weight and taken once daily with food; duration is usually 8 weeks.
Common side effects
- Headache
- Fatigue
- Nausea
- Diarrhea
Important warnings
- Not for people with moderate or severe liver impairment.
- Can reactivate hepatitis B; screening is needed before treatment.
- Do not use with rifampin or atazanavir.
- Check all medicines for interactions before starting treatment.
Pregnancy
Human pregnancy information is limited; discuss potential risks and benefits with a healthcare professional.
Breastfeeding
It is unknown whether these medicines pass into breast milk; discuss treatment with a healthcare professional.
Interactions
- Rifampin: do not use together.
- Atazanavir: do not use together.
- Some seizure medicines, including carbamazepine, can reduce antiviral levels.
- Can increase levels of some statins, including atorvastatin.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.