About gepotidacin mesylate
Triazaacenaphthylene antibacterial
Used for
- Treatment of uncomplicated urinary tract infections in adult women and girls aged 12 years and older.
Usual adult dose
1,500 mg by mouth twice daily for five days.
Usual dose in children
For ages 12 and older: 1,500 mg twice daily for five days; not established for younger children.
Common side effects
- Diarrhea
- Nausea
- Abdominal pain
- Headache
Important warnings
- Use only for susceptible bacteria; resistance can limit effectiveness.
- Not recommended when kidney function is severely reduced.
- Can cause antibiotic-associated diarrhea, including potentially severe colitis.
- Seek medical assessment for allergic reactions or severe skin symptoms.
Pregnancy
Human pregnancy data are limited; use requires consideration of potential risks and benefits.
Breastfeeding
It is unknown whether gepotidacin passes into breast milk; breastfeeding effects are uncertain.
Interactions
- Avoid with medicines that prolong the QT interval, due to abnormal heart rhythm risk.
- Strong CYP3A4 inhibitors can increase gepotidacin levels; dose adjustment may be needed.
- Strong CYP3A4 inducers can reduce levels and treatment effectiveness.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.