About gefitinib
Epidermal growth factor receptor inhibitor
Used for
- Treats certain advanced non-small-cell lung cancers with EGFR mutations.
Usual adult dose
250 mg by mouth once daily, with or without food.
Common side effects
- Diarrhea
- Skin rash or acne
- Dry skin
- Nausea
Important warnings
- Used for cancers with specific EGFR mutations; testing is required.
- Can rarely cause severe lung inflammation or breathing problems.
- May cause liver injury; liver tests may be needed.
- Can cause severe diarrhea or eye problems.
Pregnancy
May harm an unborn baby. Avoid use during pregnancy; effective contraception is recommended during treatment and for at least two weeks afterward.
Breastfeeding
Breastfeeding is not recommended during treatment and for at least two weeks after the last dose.
Interactions
- Stomach-acid reducing medicines can lower gefitinib levels.
- Strong CYP3A4 inducers, such as rifampicin, can reduce its effect.
- Warfarin may increase bleeding risk; closer monitoring may be needed.
- Grapefruit may affect gefitinib levels.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.