About fruquintini b
Vascular endothelial growth factor receptor inhibitor
Used for
- Previously treated colorectal cancer that has spread to other organs
Usual adult dose
5 mg once daily for 21 days, followed by 7 days off; repeat every 28 days. Dose reductions may be needed.
Common side effects
- High blood pressure
- Tiredness
- Painful redness or peeling of hands and feet
- Protein in urine
Important warnings
- Can cause serious bleeding
- Can cause holes in the stomach or bowel
- Can cause liver injury
- Can impair wound healing; treatment interruption is required around major surgery
Pregnancy
Can harm an unborn baby. Effective contraception is required during treatment and for two weeks after the last dose.
Breastfeeding
Do not breastfeed during treatment or for two weeks after the last dose.
Interactions
- Rifampicin and other strong enzyme inducers can reduce effectiveness
- Carbamazepine and phenytoin can reduce effectiveness
- St John's wort can reduce effectiveness
- Avoid moderate CYP3A enzyme inducers
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.