About flutamide
Nonsteroidal antiandrogen
Used for
- Used with a hormone-releasing medicine to treat advanced prostate cancer.
Usual adult dose
250 mg by mouth three times daily, usually with a gonadotropin-releasing hormone medicine.
Common side effects
- Diarrhea, nausea, vomiting, or loss of appetite
- Hot flashes or reduced sex drive
- Breast tenderness or enlargement
- Liver injury, which can be severe
Important warnings
- Can cause serious, sometimes fatal, liver damage; liver tests are required.
- Seek urgent care for yellow skin, dark urine, severe fatigue, or persistent abdominal pain.
- Usually started with a hormone-releasing medicine; follow the prescribed treatment plan.
- May cause anemia or other blood-cell changes.
Pregnancy
Not used in pregnancy; it may harm a developing fetus.
Breastfeeding
Not used during breastfeeding; it may harm a nursing infant.
Interactions
- Warfarin: flutamide may increase anticoagulant effects; monitoring and dose adjustment may be needed.
- Other medicines that can injure the liver may increase liver-damage risk.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.